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All functions

POU5F1_target_conservation
Cross-species conservation measures of the target genes in the POU5F1 module
addDirectionality()
Add directionality of interactions
applyPower()
Apply soft-thresholding
assignInitialModules()
Assign initial modules
calculateEdgeDivergence()
Calculate the divergence of intramodular edges
calculateEigengenes()
Calculate module eigengenes
calculatePresStats()
Calculate preservation statistics
calculateTreeStats()
Calculate tree statistics across all modules
comparePresStats()
Compare preservation statistics
consensus_network
Consensus network
convertPresToDist()
Convert preservation statistics to distances across all modules
convertToDT()
Convert a list of igraphs to a list of data tables
convertToGraph()
Convert a list of data frames to a list of igraphs
createConsensus()
Create consensus network
createRandomModules()
Create random modules
dist
Distance measures of the pruned modules
dist_jk
Distance measures of the original and jackknifed pruned modules
eigengenes
Eigengenes
eigengenes_per_species
Eigengenes per species
filterModuleTrees()
Filter modules based on their tree representations
findConservedDivergedModules()
Find conserved and diverged modules
findConservedDivergedTargets()
Find conserved and diverged target genes within a module
fitTreeStatsLm()
Fit (weighted) linear model between tree-based statistics
genes
All genes
getRegulators()
Get transcriptional regulators
getTreeDf()
Convert a tree to a data frame
gtf_list
List of genomic annotations
image_TRs
IMAGE transcriptional regulators
initial_modules
Initial modules
jaspar_core_TRs
JASPAR 2024 vertebrate core transcriptional regulators
jaspar_unvalidated_TRs
JASPAR 2024 unvalidated transcriptional regulators
lm_overall
Linear model for the characterization of overall module conservation
loadNetworks()
Load networks as a list of igraph objects
module_conservation_overall
Cross-species conservation measures per module
network_list
List of networks
network_list_raw
List of raw networks
normalizeEdgeWeights()
Normalize edge weights between 0 and 1
plotConservedDivergedModules()
Plot module conservation
plotConservedDivergedTargets()
Plot target conservation
plotDistMats()
Plot the distance matrices of replicates based on module connectivity patterns
plotEigengeneHeatmap()
Plot module eigengenes as a heatmap
plotEigengenesAlongPseudotime()
Plot module eigengenes along a pseudotime trajectory
plotEigengenesViolin()
Plot eigengene distributions per cell type and species
plotExprAlongPseudotime()
Plot expression profiles along a pseudotime trajectory
plotExprHeatmap()
Plot expression profiles as a heatmap
plotExprViolin()
Plot expression distributions per cell type and species
plotModuleSizeDistribution()
Plot the distribution of module sizes
plotNetworks()
Plot the networks of modules
plotPresStatDistributions()
Plot the distributions of preservation statistics
plotPresStats()
Plot cross-species VS within-species preservation statistics per species pair
plotSumEigengeneHeatmap()
Plot summarized eigengenes as a heatmap
plotSumEigengenesLine()
Plot summarized eigengenes as a line plot
plotSumExprHeatmap()
Plot summarized expression profiles as a heatmap
plotSumExprLine()
Plot summarized expression profiles as a line plot
plotTreeStatDistributions()
Plot the distributions of tree-based statistics
plotTreeStats()
Plot tree-based statistics against each other
plotTrees()
Plot the tree representations of modules
pres_stats
Preservation statistics of the pruned modules
pres_stats_jk
Preservation statistics of the original and jackknifed pruned modules
pruneModules()
Prune modules
pruneModules_UIK_adj()
Prune modules based on the regulator-target adjacencies using dynamic filtering
pruneModules_UIK_adj_kIM()
Prune modules based on the regulator-target adjacencies and intramodular connectivities using dynamic filtering
pruneModules_topN()
Prune modules based on the regulator-target adjacencies by keeping a fixed number of top targets
pruned_modules
Pruned modules
random_dist_jk
Distance measures of the the original and jackknifed random modules
random_modules
Random modules
random_pres_stats
Preservation statistics of the random modules
random_pres_stats_jk
Preservation statistics of the the original and jackknifed random modules
random_tree_stats
Tree-based statistics of the random modules
random_tree_stats_jk
Tree-based statistics of the original and jackknifed random modules
random_trees_jk
Trees of the original and jackknifed random modules
reconstructTrees()
Reconstruct trees across all modules
regulators
Transcriptional regulators
removeOverlappingGenePairs()
Remove gene pairs with overlapping annotations
replicate2species
Replicate-species conversion
scaleFreeFitRSquared()
Calculate R2 value of the scale-free model fit for the provided connectivities
sce
SCE object of the primate neural differentiation dataset
selectPower()
Select power for scale-free transfrmation
summarizeJackknifeStats()
Summarize jackknife statistics
summarizeStat()
Summarize values of a statistic
testPowers()
Test soft-thresholding power values
tree
Phylogenetic tree
tree_stats
Tree-based statistics of the pruned modules
tree_stats_jk
Tree-based statistics of the original and jackknifed pruned modules
trees
Trees of the pruned modules
trees_jk
Trees of the original and jackknifed pruned modules