
Package index
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POU5F1_target_conservation - Cross-species conservation measures of the target genes in the POU5F1 module
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addDirectionality() - Add directionality of interactions
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applyPower() - Apply soft-thresholding
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assignInitialModules() - Assign initial modules
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calculateEdgeDivergence() - Calculate the divergence of intramodular edges
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calculateEigengenes() - Calculate module eigengenes
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calculatePresStats() - Calculate preservation statistics
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calculateTreeStats() - Calculate tree statistics across all modules
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comparePresStats() - Compare preservation statistics
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consensus_network - Consensus network
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convertPresToDist() - Convert preservation statistics to distances across all modules
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convertToDT() - Convert a list of igraphs to a list of data tables
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convertToGraph() - Convert a list of data frames to a list of igraphs
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createConsensus() - Create consensus network
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createRandomModules() - Create random modules
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dist - Distance measures of the pruned modules
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dist_jk - Distance measures of the original and jackknifed pruned modules
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eigengenes - Eigengenes
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eigengenes_per_species - Eigengenes per species
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filterModuleTrees() - Filter modules based on their tree representations
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findConservedDivergedModules() - Find conserved and diverged modules
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findConservedDivergedTargets() - Find conserved and diverged target genes within a module
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fitTreeStatsLm() - Fit (weighted) linear model between tree-based statistics
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genes - All genes
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getRegulators() - Get transcriptional regulators
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getTreeDf() - Convert a tree to a data frame
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gtf_list - List of genomic annotations
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image_TRs - IMAGE transcriptional regulators
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initial_modules - Initial modules
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jaspar_core_TRs - JASPAR 2024 vertebrate core transcriptional regulators
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jaspar_unvalidated_TRs - JASPAR 2024 unvalidated transcriptional regulators
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lm_overall - Linear model for the characterization of overall module conservation
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loadNetworks() - Load networks as a list of igraph objects
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module_conservation_overall - Cross-species conservation measures per module
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network_list - List of networks
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network_list_raw - List of raw networks
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normalizeEdgeWeights() - Normalize edge weights between 0 and 1
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plotConservedDivergedModules() - Plot module conservation
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plotConservedDivergedTargets() - Plot target conservation
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plotDistMats() - Plot the distance matrices of replicates based on module connectivity patterns
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plotEigengeneHeatmap() - Plot module eigengenes as a heatmap
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plotEigengenesAlongPseudotime() - Plot module eigengenes along a pseudotime trajectory
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plotEigengenesViolin() - Plot eigengene distributions per cell type and species
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plotExprAlongPseudotime() - Plot expression profiles along a pseudotime trajectory
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plotExprHeatmap() - Plot expression profiles as a heatmap
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plotExprViolin() - Plot expression distributions per cell type and species
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plotModuleSizeDistribution() - Plot the distribution of module sizes
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plotNetworks() - Plot the networks of modules
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plotPresStatDistributions() - Plot the distributions of preservation statistics
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plotPresStats() - Plot cross-species VS within-species preservation statistics per species pair
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plotSumEigengeneHeatmap() - Plot summarized eigengenes as a heatmap
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plotSumEigengenesLine() - Plot summarized eigengenes as a line plot
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plotSumExprHeatmap() - Plot summarized expression profiles as a heatmap
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plotSumExprLine() - Plot summarized expression profiles as a line plot
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plotTreeStatDistributions() - Plot the distributions of tree-based statistics
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plotTreeStats() - Plot tree-based statistics against each other
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plotTrees() - Plot the tree representations of modules
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pres_stats - Preservation statistics of the pruned modules
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pres_stats_jk - Preservation statistics of the original and jackknifed pruned modules
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pruneModules() - Prune modules
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pruneModules_UIK_adj() - Prune modules based on the regulator-target adjacencies using dynamic filtering
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pruneModules_UIK_adj_kIM() - Prune modules based on the regulator-target adjacencies and intramodular connectivities using dynamic filtering
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pruneModules_topN() - Prune modules based on the regulator-target adjacencies by keeping a fixed number of top targets
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pruned_modules - Pruned modules
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random_dist_jk - Distance measures of the the original and jackknifed random modules
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random_modules - Random modules
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random_pres_stats - Preservation statistics of the random modules
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random_pres_stats_jk - Preservation statistics of the the original and jackknifed random modules
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random_tree_stats - Tree-based statistics of the random modules
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random_tree_stats_jk - Tree-based statistics of the original and jackknifed random modules
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random_trees_jk - Trees of the original and jackknifed random modules
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reconstructTrees() - Reconstruct trees across all modules
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regulators - Transcriptional regulators
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removeOverlappingGenePairs() - Remove gene pairs with overlapping annotations
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replicate2species - Replicate-species conversion
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scaleFreeFitRSquared() - Calculate R2 value of the scale-free model fit for the provided connectivities
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sce - SCE object of the primate neural differentiation dataset
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selectPower() - Select power for scale-free transfrmation
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summarizeJackknifeStats() - Summarize jackknife statistics
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summarizeStat() - Summarize values of a statistic
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testPowers() - Test soft-thresholding power values
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tree - Phylogenetic tree
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tree_stats - Tree-based statistics of the pruned modules
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tree_stats_jk - Tree-based statistics of the original and jackknifed pruned modules
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trees - Trees of the pruned modules
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trees_jk - Trees of the original and jackknifed pruned modules