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Correlation of intramodular connectivities (cor_kIM) per replicate pair and random module. The preservation statistic cor.kIM quantifies how well the connectivity patterns are preserved between the networks of two replicates, mathematically it is the correlation of the intramodular connectivities per module member gene in the network of the 1st replicate VS the intramodular connectivities per module member gene in the network of the 2nd replicate. This statistic was calculated for all possible jackknifed versions of the modules, each of which was created by removing a target gene assigned to the given module (the regulators were never excluded). Each jackknifed module was compared between all posible pairs of replicates, both within and across species, resulting in a cor.kIM value per jackknifed module version and replicate pair. Finally, the cor.kIM values were summarized per module and replicate pair by taking the median and its 95% confidence interval across all jackknifed module versions.

Usage

random_pres_stats

Format

A data frame with 252 rows and 10 columns:

regulator

Character, transcriptional regulator.

module_size

Module size, the numer of target genes assigned to a regulator.

replicate1, replicate2

The names of the replicates compared.

species1, species2

The names of the species 'replicate1' and 'replicate2' belongs to, respectively.

cor_kIM

The median of cor.kIM across all jackknifed versions of the module.

var_cor_kIM

The variance of cor.kIM across all jackknifed versions of the module.

lwr_cor_kIM

The lower bound of the 95% confidence interval of cor.kIM calculated by jackknifing.

upr_cor_kIM

The upper bound of the 95% confidence interval of cor.kIM calculated by jackknifing.

cor_adj

The median of cor.adj across all jackknifed versions of the module.

var_cor_adj

The variance of cor.adj across all jackknifed versions of the module.

lwr_cor_adj

The lower bound of the 95% confidence interval of cor.adj calculated by jackknifing.

upr_cor_adj

The upper bound of the 95% confidence interval of cor.adj calculated by jackknifing.